PUR1800 Clinical Advisory Board

William J. Calhoun, MD
Chair - PUR1800 Clinical Advisory Board

Dr. Calhoun earned his medical degree at Hershey Medical Center, Pennsylvania State University, in Hershey, Pennsylvania. He completed his fellowship in Pulmonary Diseases at the University of Vermont and his fellowship in Allergy – Clinical Immunology at the University of Wisconsin in Madison. He holds a certificate in Medical and Health Care Management from Rice University Jesse Jones School of Business in Houston, Texas. ...see more

Dr. Calhoun was a founding member of the US Severe Asthma Research Program, a member of the US Asthma Clinical Research Network, and is an experienced clinical trialist. He served on, and then chaired, the Pulmonary Allergy Drug Advisory Committee for the US FDA, and now serves ad hoc on many FDA Advisory Committees. He was a standing member of the NIH IRAP study section and has served ad hoc on other NIH study sections. He has chaired many NIH study sections in pulmonary diseases. He is a member of the American Thoracic Society and a fellow of the American Academy of Asthma, Allergy, & Immunology (AAAAI), the American College of Asthma, Allergy, and Immunology (ACAAI), the American College of Physicians (ACP), and the American College of Chest Physicians (ACCP).

Dr. Calhoun has served on the editorial board of the Journal of Allergy and Clinical Immunology and is currently section editor of Current Allergy and Asthma Reports. He also serves as a journal reviewer for top tier journals, including the New England Journal of Medicine, the American Journal of Physiology, the Journal of Allergy and Clinical Immunology, the Journal of the American Medical Association, and Chest. He has published over 180 peer-reviewed articles and book chapters.

His clinical and research interests include the causes and mechanisms of severe asthma and immunologic lung diseases and novel therapeutic approaches for these conditions.
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Rusty Clayton, DO
Strategic Advisor and Clinical Programs Medical Director

Dr. Clayton leverages over 15 years of executive experience in pharmaceutical, biologics, and medical device development and commercialization as a consultant in clinical development, medical affairs, and regulatory affairs. Prior to becoming a consultant, Dr. Clayton was the ...see more chief medical officer at Alcresta Therapeutics, a medical device company. While at Alcresta, Dr. Clayton led clinical development and medical affairs, overseeing the design and execution of pivotal clinical studies as well as developing a medical affairs capability in support of a new product launch. Prior to Alcresta Therapeutics, Dr. Clayton was the senior vice president of research and development at Discovery Labs, a pharmaceutical and medical device company, where he led the scientific and regulatory efforts leading to the marketing authorization of Discovery’s first product. Dr. Clayton is a board certified pediatric pulmonologist who practiced at St. Christopher’s Hospital for Children and the Children’s Hospital of Philadelphia prior to beginning his career in the pharmaceutical, biologics, and medical device industry. Dr. Clayton graduated from the Philadelphia College of Osteopathic Medicine. ...see less

Wisla Wedzicha, MD

Fernando Martinez, MD