iSPERSE™

Our innovative particle engineering technology creates dry powder, which solves limitations of conventional inhaled technologies and expands the universe of inhalable drug therapies.

iSPERSE™iSPERSE™

iSPERSE is a proprietary technology that allows a broad range of drugs to be formulated as small, dense, and dispersible particles for highly efficient drug delivery and deep penetration into the lungs.

iSPERSE™iSPERSE™

iSPERSE can efficiently deliver small molecules, drug combinations, peptides, proteins, and nucleic acids via the respiratory system for the treatment of both respiratory and non-respiratory diseases.

The
Benefits of

iSPERSE™ White

virus

Can be used with a broad range of drugs, small molecule to biologic

lungs

Can deliver large doses into lungs (tens of milligrams) with high lung delivery efficiency

inhaler

Can be used with any device (ie, metered-dose, reservoir, or blister-based inhalers)

liver

Avoids first-pass effect and systemic side-effects, with improved PK profile compared to oral delivery

people

Can be administered to all patients due to its high dispersibility over a wide range of flow rates allowing for efficient penetration deep into the lung

chart

Broad IP portfolio into 2030s

The Initial
Focus of iSPERSE– Respiratory Diseases

Applying
iSPERSE™

PULMATRiX is currently
studying the potential for iSPERSE
to improve the lives of patients living with:

Allergic
Bronchopulmonary Aspergillosis
(ABPA)

What is ABPA?

Acute Exacerbations
of Chronic Obstructive
Pulmonary Disease
(AECOPD)

What is AECOPD?

Idiopathic
Pulmonary
Fibrosis
(IPF)